Certainly! Here is some detailed information about injectable treatments for HIV from the knowledge base:
Injectable Medication for HIV Treatment
- Cabenuva
- Components: Combination of cabotegravir and rilpivirine.
- Approval: Approved by the U.S. Food and Drug Administration (FDA) in January.
- Administration: Show Full Answer
Certainly! Here is some detailed information about injectable treatments for HIV from the knowledge base:
Injectable Medication for HIV Treatment
- Cabenuva:
- Components: Combination of cabotegravir and rilpivirine.
- Approval: Approved by the U.S. Food and Drug Administration (FDA) in January.
- Administration: Given once per month as an injection into the muscle of the buttocks. Future regimens may extend to every eight weeks.
- Purpose: Designed to replace daily oral ART regimens for people with well-controlled HIV (virologically suppressed or “undetectable”).
- Oral Tablet Lead-In: Before starting Cabenuva, individuals typically take oral formulations of cabotegravir (Vocabria) and rilpivirine (Edurant) for one month to ensure tolerance and monitor side effects.
Benefits of Injectable Treatments
- Reduced Frequency: Administered every one to two months, reducing the burden of daily pills.
- Adherence: Clinical trials show high adherence rates, with 97% of injections occurring within the required timeframe.
- Privacy and Convenience: Helps address issues like anxiety over missing doses and privacy concerns related to daily medication.
Side Effects
- Common Side Effects: Injection-site reactions are the most common, though few side effects have been severe.
Injectable Medication for HIV Prevention
- Apretude: Another injectable option for HIV prevention, administered similarly to Cabenuva.
Challenges with Oral ART
- Adherence Issues: About 30% of people living with HIV have trouble sticking to their treatment, which can lead to drug-resistant HIV.
- Daily Administration: Oral ART must be taken daily, sometimes multiple times per day, which can be challenging for some individuals.
Injectable treatments like Cabenuva and Apretude offer promising alternatives for those who struggle with daily oral medications, providing a more manageable and discreet option for HIV treatment and prevention.
August 1
Im on cabenuva and loving it! Best switch ever!
March 23
They have been lots of people here. That made the change look in the questions and answers section. You may find your question there
February 3